The architecture choice changes the DC side of the system, and the DC side is where the recognised rooftop PV fire risk sits. A string of modules carries several hundred volts in daylight, present continuously with no zero-crossing, so a loose, corroded or badly made DC connection can strike an arc that does not self-extinguish the way an AC fault does. RC62, the joint fire-and-rescue and industry guidance, and the wider RISCAuthority fire-safety literature are written around this DC hazard, and the inverter architecture decides how much DC cabling exists and how far it runs.
A string design distributes the inverters across the roof, so the high-voltage DC runs are short and local to each unit and the array converts to AC close to the panels. The trade is a larger count of DC string connections and connectors, each a potential fault point that has to be made with one connector type, mated like-for-like, with factory-style crimps. A central design has far fewer connections, but it pulls long high-voltage DC runs across the whole array to one unit beside the transformer, so a greater length of the system stays live at high DC voltage and further from the point of isolation. Neither is safer in the abstract. They move the risk to different places, and the survey decides which profile suits the building, the roof construction and the access a fire service would need.
This is also where isolation and shutdown differ in practice. Because daylight keeps the DC side energised, a fault cannot be cleared by switching the building off, so clear, labelled DC isolation matters under either architecture. The wiring-regulation basis for those terminations and isolation points is set out in our guide to BS 7671 and solar, and the fire-safety detail of the DC side sits in our note on RC62 and rooftop fire risk. We design the DC layout, the connector regime and the isolation strategy to the same standard whichever architecture the roof calls for, because the choice changes where the DC risk lives, not whether it has to be controlled.